Research in Engineered Tissue Model System focuses on cell and engineered tissue mechanics with application in cardiovascular regenerative medicine. The goal is to integrate the various areas of differential mechano-regulation of stem cells towards the cardiovascular phenotype as well as the synthesis of viable engineered cardiovascular tissues, particularly, heart valves.  This goal fragments into multiple areas of study:

  • Tissue engineered heart valve replacement for critical congenital mitral and aortic valve disease,
  • Leaflet repair using engineered heart valve tissues and
  • Bioreactor development to create engineered cardiovascular tissue model systems to facilitate therapeutic discovery.

Dr. Joshua Hutcheson, Assistant Professor, Biomedical Engineering, Florida International University

Joshua Hutcheson, Ph.D.

Assistant Professor & Acting Graduate Advisor

Download Curriculum VitaeResearch Interests: Cardiovascular disease and mechanobiology, Cell-cell and cell-matrix interactions, Tissue engineering, Molecular imaging
Research Advancements: Joshua Hutcheson studies cardiovascular disease mechanisms.
Research Area: Engineered Tissue Model Systems
Lab: Cardiovascular Matrix Remodeling Laboratory

Office: EC 2612
Phone: (305) 348-0157

Website: https://bme.fiu.edu/people/faculty-instructors/joshua-hutcheson/


Dr. Sharan Ramaswamy, Associate Professor, Biomedical Engineering, Florida International University

Sharan Ramaswamy, Ph.D.

Associate Professor

Download Curriculum VitaeResearch Interests: Cell and tissue mechanics with application in cardiovascular regenerative medicine
Research Advancements: Biomechanically-derived diagnostics and regenerative therapies for cardiovascular medicine.
Research Area: Engineered Tissue Model Systems
Lab: CV-PEUTICS – Cardiovascular Therapeutics Laboratory

Office: EC 2614
Phone: (305) 348-2532

Website: https://bme.fiu.edu/people/faculty-instructors/sharan-ramaswamy/


Dr. Nikolaos Tsoukias, Associate Professor, Biomedical Engineering, Florida International University

Nikolaos Tsoukias, Ph.D.

Associate Professor

Download Curriculum VitaeResearch Interests: Computational and mathematical modeling, biotransport, signal transduction, cardiovascular and respiratory systems physiology
Research Advancements: Nikolaos Tsoukias studies neuromuscular coupling.
Research Area: Engineered Tissue Model Systems
Lab: Vascular Physiology and Biotransport

Office: EC 2674
Phone: (305) 348-7291

Website: https://tsoukias.fiu.edu