Research in Engineered Tissue Model System focuses on cell and engineered tissue mechanics with application in cardiovascular regenerative medicine. The goal is to integrate the various areas of differential mechano-regulation of stem cells towards the cardiovascular phenotype as well as the synthesis of viable engineered cardiovascular tissues, particularly, heart valves.  This goal fragments into multiple areas of study:

  • Tissue engineered heart valve replacement for critical congenital mitral and aortic valve disease,
  • Leaflet repair using engineered heart valve tissues and
  • Bioreactor development to create engineered cardiovascular tissue model systems to facilitate therapeutic discovery.

Joshua Hutcheson, Ph.D.

Assistant Professor

cv-icon-36

Research Interests: Cardiovascular disease and mechanobiology, Cell-cell and cell-matrix interactions, Tissue engineering, Molecular imaging
Research Advancements: Joshua Hutcheson studies cardiovascular disease mechanisms.
Research Area: Basic Research in Tissue Engineering Model Systems
Lab: Cardiovascular Matrix Remodeling Laboratory

Office: EC 2612
Phone: (305) 348-0157

Website: https://bme.fiu.edu/people/faculty-instructors/joshua-hutcheson/


sharan-ramaswamy-fiu-college-engineering-computing-300x300

Sharan Ramaswamy, Ph.D.

Associate Professor

cv-icon-36

Research Interests: Cell and engineered tissue mechanics with application in cardiovascular regenerative medicine
Research Advancements: Sharan Ramaswamy advances biomechanically-derived diagnostics and regenerative therapies for cardiovascular medicine.
Research Area: Basic Research in Tissue Engineering Model Systems
Lab: Tissue Engineered Mechanics, Imaging, and Materials (TEMIM)

Office: EC 2614
Phone: (305) 348-2532

Website: https://bme.fiu.edu/people/faculty-instructors/sharan-ramaswamy/


Tsoukias

Nikolaos Tsoukias, Ph.D.

Associate Professor

cv-icon-36

Research Interests: Computational and mathematical modeling, biotransport, signal transduction, cardiovascular and respiratory systems physiology
Research Advancements: Nikolaos Tsoukias studies neuromuscular coupling.
Research Area: Basic Research in Tissue Engineering Model Systems
Lab: Vascular Physiology and Biotransport

Office: EC 2674
Phone: (305) 348-7291

Website: https://tsoukias.fiu.edu