Research in Engineered Tissue Model System focuses on cell and engineered tissue mechanics with application in cardiovascular regenerative medicine. The goal is to integrate the various areas of differential mechano-regulation of stem cells towards the cardiovascular phenotype as well as the synthesis of viable engineered cardiovascular tissues, particularly, heart valves.  This goal fragments into multiple areas of study:

  • Tissue engineered heart valve replacement for critical congenital mitral and aortic valve disease,
  • Leaflet repair using engineered heart valve tissues and
  • Bioreactor development to create engineered cardiovascular tissue model systems to facilitate therapeutic discovery.

Dr. Joshua Hutcheson, Assistant Professor, Biomedical Engineering, Florida International University

Joshua Hutcheson, Ph.D.

Assistant Professor

Download Curriculum VitaeResearch Interests: Cardiovascular disease and mechanobiology, Cell-cell and cell-matrix interactions, Tissue engineering, Molecular imaging
Research Advancements: Joshua Hutcheson studies cardiovascular disease mechanisms.
Research Area: Engineered Tissue Model Systems
Lab: Cardiovascular Matrix Remodeling Laboratory

Office: EC 2612
Phone: (305) 348-0157

Website: https://bme.fiu.edu/people/faculty-instructors/joshua-hutcheson/


Dr. Sharan Ramaswamy, Associate Professor, Biomedical Engineering, Florida International University

Sharan Ramaswamy, Ph.D.

Associate Professor | Certified Hybrid Instructor

Download Curriculum VitaeResearch Interests: Cell and tissue mechanics with application in cardiovascular regenerative medicine
Research Advancements: Biomechanically-derived diagnostics and regenerative therapies for cardiovascular medicine.
Research Area: Engineered Tissue Model Systems
Lab: CV-PEUTICS – Cardiovascular Therapeutics Laboratory

Office: EC 2614
Phone: (305) 348-2532

Website: https://bme.fiu.edu/people/faculty-instructors/sharan-ramaswamy/


Dr. Nikolaos Tsoukias, Associate Professor, Biomedical Engineering, Florida International University

Nikolaos Tsoukias, Ph.D.

Associate Professor

Download Curriculum VitaeResearch Interests: Computational and mathematical modeling, biotransport, signal transduction, cardiovascular and respiratory systems physiology
Research Advancements: Nikolaos Tsoukias studies neuromuscular coupling.
Research Area: Engineered Tissue Model Systems
Lab: Vascular Physiology and Biotransport

Office: EC 2674
Phone: (305) 348-7291

Website: https://bme.fiu.edu/people/faculty-instructors/nikolaos-tsoukias