Research Interests: Biomechanics, Biomaterials, Medical Device product development, design, and manufacturing. Computational modeling of cardiovascular and related diseases for improved device designs and clinical intervention strategies.

Research Interests: Cardiovascular disease and mechanobiology, Cell-cell and cell-matrix interactions, Tissue engineering, Molecular imaging
Research Advancements: Joshua Hutcheson studies cardiovascular disease mechanisms.
Research Area: Engineered Tissue Model Systems
Lab: Cardiovascular Matrix Remodeling Laboratory

Research Interests: Biophotonics, Ultrasound, and Medical Instrumentation
Research Advancements: Wei-Chiang Lin develops smart intraoperative guidance systems for surgery.
Research Area: Diagnostic Bioimaging Sensor Systems
Lab: Biomedical Engineering Creative Lab: W[CL]2 (Under Construction)

Research Interests: Neuroinflammation and neurodegeneration in traumatic brain injury (TBI), blood-brain barrier (BBB) disruption and transmigration of immune cells in TBI, neurovascular dysfunction in alcohol use disorder (AUD), gene and peptide-based therapeutic strategies for TBI and AUD, and survival surgeries and rodent behavioral assessments.

Research Advancements: neuronal and neurovascular dysfunction in TBI and chronic alcohol exposure using advanced molecular biology tools, high-resolution microscopy and imaging, cerebral blood flow analysis, optogenetics, and electrophysiology. The research integrates gene and peptide therapies to promote neurovascular repair and cognitive recovery. Using in vivo and in vitro injury models, the lab applies viral gene transfer, CRISPR/Cas9 editing, conditional knockouts, pharmacological interventions, survival surgeries, and behavioral assays.

Research Area: molecular and cellular mechanisms underlying axonal regeneration, neuronal repair, and survival following traumatic brain injury (TBI), aiming to develop effective therapeutic strategies for neurological recovery. His research explores signaling pathways that limit neuronal regeneration in central nervous system (CNS) injury. Additionally, Dr. Muneer investigates blood-brain barrier disruption and its role in neurovascular inflammation and neurological disorders such as stroke linked to alcohol use disorder.

Lab: The Laboratory of CNS Injury and Molecular Therapy

Research Advancements: Electronic and Bioelectronic Packaging, Flex and 3D packaging with Heterogeneous System Integration for Emerging Biomedical, Communication and Computing systems, Wearable and Implantable Medical Devices, Advanced Passive Components, Vertical Power Delivery, 5G and 6G Systems Packaging, Antenna Sensor Integration, Power and Data Telemetry, Hermetic Packaging, Interconnects and Connectors
Research Area: Therapeutic and Reparative Neurotechnology
Lab: Bioelectronic and Electronic Packaging Lab

Research Interests: Biophysical Foundations of Neuroimaging in Normal Aging and Brain Disorders
Research Advancements: Jorge Riera is making strides in treating multiple brain disorders.
Research Area: Therapeutic and Reparative Neurotechnology
Lab: Neuronal Mass Dynamics Laboratory

Research Interests: Mechanisms of seizure generation, propagation, generalization and termination, Excitotoxic and metabolic abnormalities in the brain as a cause and/or consequence of seizures, Cellular and molecular processes involved in the neurobiology of sleep in health and disease and Calcium signaling in neurons and astrocytes in the context of excitatory and inhibitory transmission
Research Advancements: Oleksii Shandra has characterized a mouse model of post-traumatic epilepsy after repeated diffuse traumatic brain injury and a technique for live brain multi-photon imaging and single-cell laser stimulation to study astrocyte calcium signaling before and after brain injury. Dr. Shandra examines electrophysiological and imaging biomarkers of epileptogenesis and pathophysiological mechanisms of the astrocyte-neuron networks.
Research Area: Arrays and silicone probes, Live brain multi-photon microscopy, Preclinical models of traumatic brain injury, sleep deprivation and acquired epilepsy, Use of transgenic mice and adeno-associated viruses, Immunohistochemical assays and confocal microscopy, MATLAB-based algorithms for spike and seizure detection and power spectrum analysis, Drug screening, Deep brain stimulation, Transcranial magnetic brain stimulation
Lab: Shandra Lab

Research Interests: Design and development of targeted drug delivery systems, nanomedicine, translational medicine, advanced particle engineering design technologies, and inhalation aerosols.
Research Advancements: Innovative inhalation aerosols as advanced inhalable microparticles/nanoparticles in airway and vascular diseases, lung surfactant multifunctional nanocarriers, nose-to-brain noninvasive therapeutic delivery, and biodegradable/biocompatible polymers for sustained-release delivery peptides/proteins/biologics.

Research Area: Research in Engineered Tissue Model Systems and Therapeutic and Reparative Neurotechnology
Lab: Mansour Lab

Research Interests: Biophysics of ion channels and transporters; Electrophysiology and imaging applied to cell/tissue physiology and drug discovery studies.
Research Advancements: Translational and experimental medicine in particular for the study of neurovascular, cardiovascular and respiratory systems physiology.
Research Area: Applied Electrophysiological techniques for the study of the neurovascular coupling.
Lab: Vascular Physiology and Biotransport

Research Interests: Heart Disease, Cardiotoxicity, Environmental Metal Exposure, Diagnostics, Signal Processing, Artificial Intelligence

Research Advancements: Developing and validating animal models of cardiovascular disease to advance our understanding of disease mechanisms, progression, and diagnostic markers, and to evaluate potential interventions.

Research Area: Engineered Tissue Model Systems
Lab: Cardiovascular Matrix Remodeling Laboratory